consider any medicines identified as nitrates, frequently prescribed for upper body soreness, or guanylate cyclase stimulators like Adempas® (riociguat) for pulmonary hypertension. Your blood pressure could fall to an unsafe amountEach on the factors shown underneath will likely be described in additional detail when you development through Each i

This metabolite incorporates a PDE selectivity profile comparable to sildenafil and an in vitro potency for PDE5 approximately fifty% of your parent drug. Plasma concentrations of this metabolite are around forty% of All those found for sildenafil, so which the metabolite accounts for approximately twenty% of sildenafil's pharmacologic outcomes.The